Cytokeratin 4 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
Synonyms
Keratin, type II cytoskeletal 4; KRT4
Gene ID
3851
Swiss Prot
P19013
Host
Rabbit
Cross Reactivity
Rat
Target
Cytokeratin 4
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
Recombinant human Cytokeratin 4 protein, around 350-480aa.
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3851
Predicted Cross Reactivity
Human
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