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Cdk2 Monoclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) . Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

Synonyms

CDKN2; p33 (CDK2) ; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2

Gene ID

1017

Swiss Prot

P24941

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Cdk2

Clonality

Monoclonal

Isotype

IgG

Clone

2E3

Conjugation

AbBy Fluor™ 594

Source

Recombinant human Cdk2 protein, around C-terminal 100aa.

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1017

Predicted Cross Reactivity

Rat

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