Cdk2 Monoclonal Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) . Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
Synonyms
CDKN2; p33 (CDK2) ; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2
Gene ID
1017
Swiss Prot
P24941
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Cdk2
Clonality
Monoclonal
Isotype
IgG
Clone
2E3
Conjugation
AbBy Fluor™ 350
Source
Recombinant human Cdk2 protein, around C-terminal 100aa.
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1017
Predicted Cross Reactivity
Rat
Curated Selection
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