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Alas1 (1G11) Recombinant Antibody

Product Specifications

Background

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

Synonyms

5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS1; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; ALAS1; ALAS3; ALASH; OK/SW-cl.121

Gene ID

211

Swiss Prot

P13196

Host

Rabbit

Cross Reactivity

Human

Target

Alas1 (1G11)

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant human Alas1 protein, around C-terminal 200aa.

Applications

WB

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

211

Available Sizes

Curated Selection

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