RAB14 Monoclonal Antibody
Product Specifications
Background
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity) . Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
Synonyms
F protein binding protein 1; bA165P4.3; FBP; GTPase RAB 14; RAB-14; RAB14 member RAS oncogene family; RAB14_HUMAN; Ras related protein Rab 14; Ras-related protein Rab-14; RP11 165P4.4; Small GTP binding protein RAB14; FBP.
Gene ID
51552
Swiss Prot
P61106
Cellular Locus
Cytoplasm
Host
Mouse
Cross Reactivity
Human
Target
RAB14
Clonality
Monoclonal
Clone
A12M1
Conjugation
Unconjugated
Source
Recombinant human RAB14.
Applications
WB
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-2000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51552
Predicted Cross Reactivity
Mouse, Chicken
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