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RAB14 Monoclonal Antibody

Product Specifications

Background

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity) . Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

Synonyms

F protein binding protein 1; bA165P4.3; FBP; GTPase RAB 14; RAB-14; RAB14 member RAS oncogene family; RAB14_HUMAN; Ras related protein Rab 14; Ras-related protein Rab-14; RP11 165P4.4; Small GTP binding protein RAB14; FBP.

Gene ID

51552

Swiss Prot

P61106

Cellular Locus

Cytoplasm

Host

Mouse

Cross Reactivity

Human

Target

RAB14

Clonality

Monoclonal

Clone

A12M1

Conjugation

Unconjugated

Source

Recombinant human RAB14.

Applications

WB

Concentration

0.5µg/µl

Dilution

WB (WB=1:500-2000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

51552

Predicted Cross Reactivity

Mouse, Chicken

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