CBX8 Monoclonal Antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiproteinPRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering chromatinheritably changed in its expressibility.
Synonyms
Chromobox protein homolog 8; HPC3; Pc3; Polycomb 3 homolog; RC1; Rectachrome 1; CBX8_HUMAN.
Gene ID
57332
Swiss Prot
Q9HC52
Cellular Locus
Nucleus
Host
Mouse
Target
CBX8
Clonality
Monoclonal
Isotype
IgG1
Clone
B2W3
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CBX8
Applications
WB, Flow-Cyt
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-1000), Flow-Cyt (Flow-Cyt=1:25)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
57332
Predicted Cross Reactivity
Human
Curated Selection
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