RCC1 Monoclonal Antibody
Product Specifications
Background
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Synonyms
Cell cycle regulatory protein; CHC 1; CHC1; Chromosome condensation 1; Chromosome condensation protein 1; Guanine nucleotide releasing protein; HERC2; Ran GEF; RanGEF; RCC 1; RCC1 I; Regulator of chromosome condensation 1; Regulator of chromosome condensation; SHEP1; RCC1_HUMAN.
Gene ID
1104
Swiss Prot
P18754
Cellular Locus
Cytoplasm, Nucleus
Host
Mouse
Cross Reactivity
Human, Mouse
Target
RCC1
Clonality
Monoclonal
Isotype
IgG1
Clone
G14A2
Conjugation
Unconjugated
Source
Recombinant human RCC1.
Applications
WB
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-2000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1104
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