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ELAVL1 Monoclonal Antibody

Product Specifications

Background

Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro.

Synonyms

HuR / ELAVL1; ELAV (embryonic lethal abnormal vision Drosophila) like 1; ELAV like 1; ELAV-like protein 1; ELAV1; ELAV1_HUMAN; Embryonic lethal abnormal vision drosophila homolog like 1; Hu Antigen R; Hu-antigen R; Hua; HuR; MelG.

Gene ID

1994

Swiss Prot

Q15717

Cellular Locus

Cytoplasm, Nucleus

Host

Mouse

Cross Reactivity

Human

Target

ELAVL1

Clonality

Monoclonal

Clone

E4F6

Conjugation

Unconjugated

Source

Recombinant human ELAVL1.

Applications

WB

Concentration

0.5µg/µl

Dilution

WB (WB=1:200-1000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

1994

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