CBX8 (12C7) Monoclonal Antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms
PC3; RC1; Chromobox protein homolog 8; Polycomb 3 homolog; hPc3; Rectachrome 1; CBX8
Gene ID
57332
Swiss Prot
Q9HC52
Host
Mouse
Cross Reactivity
Human
Target
CBX8
Clonality
Monoclonal
Isotype
IgG1
Clone
12C7
Conjugation
Unconjugated
Source
This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.
Applications
WB
Purification
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
57332
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