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CBX8 (12C7) Monoclonal Antibody

Product Specifications

Background

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Synonyms

PC3; RC1; Chromobox protein homolog 8; Polycomb 3 homolog; hPc3; Rectachrome 1; CBX8

Gene ID

57332

Swiss Prot

Q9HC52

Host

Mouse

Cross Reactivity

Human

Target

CBX8

Clonality

Monoclonal

Isotype

IgG1

Clone

12C7

Conjugation

Unconjugated

Source

This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.

Applications

WB

Purification

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Concentration

0.5µg/µl

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

57332

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