ACE2 (1C4) Monoclonal Antibody
Product Specifications
Background
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. (Microbial infection) Acts as a receptor for SARS coronavirus/SARS-CoV and human coronavirus NL63/HCoV-NL63.
Synonyms
ACEH; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15; ACE2; UNQ868/PRO1885
Gene ID
59272
Swiss Prot
Q9BYF1
Host
Mouse
Cross Reactivity
Human
Immunogen
631-805/805
Target
ACE2
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
1C4
Conjugation
Unconjugated
Source
Purified His-tagged ACE2 protein was used to produced this monoclonal antibody.
Applications
WB, ELISA, IHC-P, IHC-F, IF, ICC/IF
Purification
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-1000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:400-800), IHC-F (IHC-F=1:400-800), IF (IF=1:100-500), ICC/IF (ICC/IF=1:100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
59272
Curated Selection
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