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Hsp90 (3C9) Monoclonal Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Synonyms

EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1

Gene ID

3320

Swiss Prot

P07900

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Hsp90

Clonality

Monoclonal

Isotype

IgG1

Clone

3C9

Conjugation

PerCP-Cy5.5

Source

This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 150-400 amino acids from human.

Applications

WB, IF

Purification

Purified by Protein G.

Excitation Emission

482nm/694nm

Concentration

0.5µg/µl

Dilution

WB (WB=1:500-1000), IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3320

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