Hsp90 (3C9) Monoclonal Antibody, PE Conjugated
Product Specifications
Background
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Synonyms
EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1
Gene ID
3320
Swiss Prot
P07900
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
Hsp90
Clonality
Monoclonal
Isotype
IgG1
Clone
3C9
Conjugation
PE
Source
This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 150-400 amino acids from human.
Applications
WB, IF
Purification
Purified by Protein G.
Excitation Emission
496,564nm/578nm
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-1000), IF (IF=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3320
Curated Selection
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