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Hsp90 (3C9) Monoclonal Antibody, APC Conjugated

Product Specifications

Background

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Synonyms

EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1

Gene ID

3320

Swiss Prot

P07900

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Hsp90

Clonality

Monoclonal

Isotype

IgG1

Clone

3C9

Conjugation

APC

Source

This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 150-400 amino acids from human.

Applications

WB, IF

Purification

Purified by Protein G.

Excitation Emission

650nm/660nm

Concentration

0.5µg/µl

Dilution

WB (WB=1:500-1000), IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3320

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