TLE4 (4C4) Monoclonal Antibody
Product Specifications
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity) .
Synonyms
ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E (spI) ; Transducin-like enhancer protein 4; Groucho-related protein 4; TLE4; KIAA1261
Gene ID
7091
Swiss Prot
Q04727
Host
Mouse
Cross Reactivity
Human
Target
TLE4
Clonality
Monoclonal
Isotype
IgM
Clone
4C4
Conjugation
Unconjugated
Source
This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.
Applications
WB
Purification
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7091
Curated Selection
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