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TLE4 (4C4) Monoclonal Antibody

Product Specifications

Background

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity) .

Synonyms

ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E (spI) ; Transducin-like enhancer protein 4; Groucho-related protein 4; TLE4; KIAA1261

Gene ID

7091

Swiss Prot

Q04727

Host

Mouse

Cross Reactivity

Human

Target

TLE4

Clonality

Monoclonal

Isotype

IgM

Clone

4C4

Conjugation

Unconjugated

Source

This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.

Applications

WB

Purification

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Concentration

0.5µg/µl

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

7091

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