BMI1 (2T6) Monoclonal Antibody
Product Specifications
Background
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Gene ID
100532731, 648
Swiss Prot
P35226
Host
Mouse
Cross Reactivity
Human
Target
BMI1
Clonality
Monoclonal
Isotype
IgG1
Clone
2T6
Conjugation
Unconjugated
Source
This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.
Applications
WB, IF
Purification
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
100532731, 648
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![1-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethanone](https://cdn.genprice.uk/products/572/7453480672493/imageurl/trc-f588585-50mg.webp)
TRC-F588585-50MG 50 mg
1-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethanone
Sign In for Pricing
View Details 
BNC741150-100 1x 100 µL
Cytokeratin 19 (KRT19/799 + KRT19/800), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details