MAP3K11 (3T1) Monoclonal Antibody
Product Specifications
Background
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Synonyms
MLK3; PTK1; SPRK; MLK-3; MEKK11; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase; MAP3K11
Gene ID
4296
Swiss Prot
Q16584
Host
Mouse
Cross Reactivity
Human
Target
MAP3K11
Clonality
Monoclonal
Isotype
IgM
Clone
3T1
Conjugation
Unconjugated
Source
This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein.
Applications
WB
Purification
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4296
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