THEM2 (9C3) Monoclonal Antibody

Product Specifications

Background

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro) . May play a role in controlling adaptive thermogenesis (By similarity) .

Synonyms

HT012; THEM2; PNAS-27; Acyl-coenzyme A thioesterase 13; Acyl-CoA thioesterase 13; Thioesterase superfamily member 2; ACOT13

Gene ID

55856

Swiss Prot

Q9NPJ3

Host

Mouse

Cross Reactivity

Human

Target

THEM2

Clonality

Monoclonal

Isotype

IgG1

Clone

9C3

Conjugation

Unconjugated

Source

This THEM2 monoclonal antibody is generated from mouse immunized with THEM2 recombinant protein.

Applications

Purification

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.