UBC9 (7A9) Monoclonal Antibody

Product Specifications

Background

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'.

Synonyms

P18; UBC9; C358B7.1; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; UBE2I; UBCE9

Gene ID

7329

Swiss Prot

P63279

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

UBC9

Clonality

Monoclonal

Isotype

IgG1

Clone

7A9

Conjugation

Unconjugated

Source

This UBC9 antibody was raised using purified GST-UBC9 fusion protein.

Applications

Purification

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.