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ZO-1 Monoclonal Antibody, FITC Conjugated

Product Specifications

Background

The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.

Synonyms

ZO1_HUMAN; Tight junction protein ZO-1; TJP1; ZO1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein

Gene ID

7082

Swiss Prot

Q07157

Cellular Locus

Cytoplasm, Cell membrane

Host

Mouse

Cross Reactivity

Human

Target

ZO-1

Clonality

Monoclonal

Isotype

IgG

Conjugation

FITC

Source

Recombinant human ZO-1 protein

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7082

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