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Myoglobin Monoclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Synonyms

MYO; MB; MGC13548; PVALB; MYG_HUMAN.

Gene ID

4151

Swiss Prot

P02144

Cellular Locus

Cytoplasm, Extracellular domain

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Myoglobin

Clonality

Monoclonal

Isotype

IgG

Clone

3A7

Conjugation

Cy5

Source

Purified Human Myoglobin (Natural Human Myoglobin protein)

Applications

IF (IHC-P), IF (ICC), IF

Purification

Purified by Protein G.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (ICC) (1:50-200), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4151

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