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Collagen II Monoclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

Synonyms

Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1 (II) ; type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1 (II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital) ; MGC131516; SEDC; Collagen alpha-1 (II) chain; Alpha-1 type II collagen; CO2A1_HUMAN.

Gene ID

1280

Swiss Prot

P02458

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Immunogen

1301-1400/1487

Target

Collagen II

Clonality

Monoclonal

Isotype

IgG

Clone

9H12

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Collagen II

Applications

IF

Purification

Purified by Protein G.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1280

Curated Selection

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