HP1 gamma Monoclonal Antibody, FITC Conjugated
Product Specifications
Background
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) . Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Synonyms
CBX 3; CBX3; Chromobox homolog 3; Chromobox protein homolog 3; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; HP1 gamma homolog; HP1Hs gamma ; Modifier 2; protein HP1-GAMMA; HP1g; M32; MGC118084; CBX3_HUMAN; Modifier 2 protein
Gene ID
11335
Swiss Prot
Q13185
Cellular Locus
Nucleus
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
HP1 gamma
Clonality
Monoclonal
Isotype
IgG
Clone
5B9
Conjugation
FITC
Source
Recombinant human HP1 gamma Protein
Applications
WB, IF (IHC-P), IF (ICC)
Purification
Purified by Protein G.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
11335
Curated Selection
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