GSK-3 Beta Monoclonal Antibody, PE Conjugated
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Synonyms
Glycogen synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK3B; GSK3B protein; GSK3beta isoform; GSK3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B_HUMAN.
Gene ID
P49841
Swiss Prot
2932
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-100/420
Target
GSK-3 Beta
Clonality
Monoclonal
Isotype
IgG
Clone
4C6
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human GSK-3 Beta
Applications
WB, IF
Purification
Purified by Protein G.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
P49841
Curated Selection
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