CREB-1 (6B4) Monoclonal Antibody, HRP Conjugated
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Synonyms
Cyclic AMP-responsive element-binding protein 1; CREB1; cAMP-responsive element-binding protein 1
Gene ID
1385
Swiss Prot
P16220
Host
Mouse
Cross Reactivity
Human, Mouse
Target
CREB-1
Clonality
Monoclonal
Isotype
IgG
Clone
6B4
Conjugation
HRP
Source
Recombinant human CREB1 protein
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1385
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