Survivin Monoclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Interacts with tubulin. Inhibitor of caspase-3 and caspase-7. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Belongs to the IAP family.?
Synonyms
API4; API-4; API 4; Survivin variant 3 alpha; Apoptosis Inhibitor 4; Apoptosis inhibitor survivin; Apoptosis inhibitor4; Baculoviral IAP repeat containing 5; Baculoviral IAP repeat containing protein 5; Baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; BIRC-5; EPR 1; EPR-1; IAP4; IAP-4; IAP 4; SVV; TIAP; BIRC5_HUMAN.??
Gene ID
332
Swiss Prot
O15392
Cellular Locus
Cytoplasm, Nucleus
Host
Mouse
Cross Reactivity
Human
Target
Survivin
Clonality
Monoclonal
Isotype
IgG
Clone
3H7
Conjugation
AbBy Fluor™ 488
Source
Recombinant human Survivin
Applications
WB, IF (ICC), IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (ICC) (1:50-200), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
332
Predicted Cross Reactivity
Rat
Curated Selection
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