Histone H3 (di methyl K36) Monoclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4 ; Histone H3.1t ; HIST3H3; HGNC:4778; H31T_HUMAN
Gene ID
8290
Swiss Prot
P68431
Cellular Locus
Nucleus
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
Histone H3 (di methyl K36)
Clonality
Monoclonal
Isotype
IgG1
Clone
3F7
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthesised methylpeptide derived from human Histone H3 around the methylation site of di methyl K36
Applications
WB, IF (IHC-P), IF (ICC)
Purification
Purified by Protein G.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8290
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