Histone H3 (di methyl K9) Monoclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4; Histone H3.1t; HIST3H3; HGNC:4778; H31T_HUMAN

Gene ID

8290

Swiss Prot

P68431

Modification Site

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Histone H3 (di methyl K9)

Clonality

Monoclonal

Isotype

IgG

Clone

5D2

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human Histone H3 (di methyl K9)

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Methylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8290

Predicted Cross Reactivity

Cow

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