Histone H3 (tri methyl K4) Monoclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4 ; Histone H3.1t ; HIST3H3; HGNC:4778; H31T_HUMAN
Gene ID
8290
Swiss Prot
P68431
Modification Site
K4
Host
Mouse
Cross Reactivity
Human, Mouse, Rat, Others
Target
Histone H3 (tri methyl K4)
Clonality
Monoclonal
Isotype
IgG
Clone
4.00E+11
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human Histone H3 (tri methyl K4)
Applications
WB, IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8290
Cross Reactivity Details
Fruit fly
Curated Selection
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