Histone H3 (di methyl K79) Monoclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4; Histone H3.1t; HIST3H3; HGNC:4778; H31T_HUMAN

Gene ID

8290

Swiss Prot

P68431

Modification Site

K79

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Histone H3 (di methyl K79)

Clonality

Monoclonal

Isotype

IgG

Clone

2A7

Conjugation

PE-Cy7

Source

KLH conjugated synthesised methylpeptide derived from human Histone H3 around the methylation site of (di methyl K79)

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Methylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8290

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