Histone H3 (di methyl K79) Monoclonal Antibody, FITC Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4; Histone H3.1t; HIST3H3; HGNC:4778; H31T_HUMAN
Gene ID
8290
Swiss Prot
P68431
Modification Site
K79
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
Histone H3 (di methyl K79)
Clonality
Monoclonal
Isotype
IgG
Clone
2A7
Conjugation
FITC
Source
KLH conjugated synthesised methylpeptide derived from human Histone H3 around the methylation site of (di methyl K79)
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8290
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