Cytokeratin 8 Monoclonal Antibody, PerCP Conjugated
Product Specifications
Background
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
Synonyms
Card2; Cardiac autoantigen 2 120kD; CK 8; CK8; CK-8; ck8; Cyk 8; cyk8; CYKER; Cytokeratin endo A; Cytokeratin-8; Cytokeratin8; DreK8; EndoA; k0; CYK8; k2c8; K2C8_HUMAN; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; Keratin8; KO; Krt 2.8; Krt 8; krt8; KRT-8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8.
Gene ID
3856
Swiss Prot
P05787
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
Cytokeratin 8
Clonality
Monoclonal
Isotype
IgG
Clone
10A8
Conjugation
PerCP
Source
Recombinant human CK8
Applications
IF (IHC-P), IF (ICC), IF
Purification
Purified by Protein G.
Excitation Emission
482nm/677nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (ICC) (1:50-200), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3856
Curated Selection
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