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Morphine (2F11) Monoclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.

Synonyms

Morphine 6.

Host

Mouse

Cross Reactivity

Others

Target

Morphine

Clonality

Monoclonal

Isotype

IgG

Clone

2F11

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated Morphine molecular modified

Applications

WB, IF

Purification

Purified by Protein G.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Cross Reactivity Details

Morphine

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