Photoclick cholesterol
Product Specifications
UNSPSC Description
Photoclick cholesterol is a sterol lipid cholesterol analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group. Photoclick cholesterol has the ability to photoaffinity label the mitochondrial outer membrane transport protein (TSPO) and is able to specifically bind cholesterol to TSPO. However, using excessive amounts of Photoclick cholesterol will reduce the photolabeling of total mitochondrial proteins and TSPO[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
others
Assay Protocol
https://www.medchemexpress.com/photoclick-cholesterol.html
Smiles
C[C@]12[C@@](C[C@H](CC2)O)([H])C3(N=N3)C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H](C)CCC(OCCCCC#C)=O)C
Molecular Weight
482.70
References & Citations
[1]Georges E, et al. Direct and specific binding of cholesterol to the mitochondrial translocator protein (TSPO) using PhotoClick cholesterol analogue[J]. The journal of biochemistry, 2021, 170(2): 239-243.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W782122/Photoclick-cholesterol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W782122/
Clinical Information
No Development Reported
CAS Number
1485490-47-8
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