Bcl-2 Monoclonal Antibody, Biotin Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
Synonyms
Apoptosis regulator Bcl-2; BCL2
Gene ID
596
Swiss Prot
P10415
Host
Mouse
Cross Reactivity
Human
Target
Bcl-2
Clonality
Monoclonal
Isotype
IgG
Clone
1A5
Conjugation
Biotin
Source
Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.
Applications
WB
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
596
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6137008-01 0.1 mL
HNF4A (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Transcription Factor HNF-4, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14) APC
Sign In for Pricing
View Details MBS6137008-02 5x 0.1 mL
HNF4A (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Transcription Factor HNF-4, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, HNF4, NR2A1, TCF14) APC
Sign In for Pricing
View Details LS023354-100ug 100 µg
HAUS5 (NM_015302) Human Over-expression Lysate
Sign In for Pricing
View Details