Bcl-2 Monoclonal Antibody, Biotin Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
Synonyms
Apoptosis regulator Bcl-2; BCL2
Gene ID
596
Swiss Prot
P10415
Host
Mouse
Cross Reactivity
Human
Target
Bcl-2
Clonality
Monoclonal
Isotype
IgG
Clone
1A5
Conjugation
Biotin
Source
Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.
Applications
WB
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
596
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL300560V 500 µL Each
VPS16 Human shRNA Lentiviral Particle (Locus ID 64601)
Sign In for Pricing
View Details 
NB600-413DL594 0.2 mL
Mouse Monoclonal Adenovirus Antibody (8C4) [DyLight 594]
Sign In for Pricing
View Details RR205779L3V 200 µL
Btg2 (NM_017259) Rat Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
GTR15188110 1 Vial
Lentiviral mouse Spn shRNA (UAS) - Lentiviral mouse Spn shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details MBS2110470-01 0.1 mL
FITC-Linked Monoclonal Antibody to Microtubule Associated Protein RP/EB Family, Member 1 (MAPRE1)
Sign In for Pricing
View Details