Bcl-2 Monoclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
Synonyms
Apoptosis regulator Bcl-2; BCL2
Gene ID
596
Swiss Prot
P10415
Host
Mouse
Cross Reactivity
Human
Target
Bcl-2
Clonality
Monoclonal
Isotype
IgG
Clone
1A5
Conjugation
APC-Cy7
Source
Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.
Applications
WB
Purification
Purified by Protein G.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
596
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740633-100 1x 100 µL
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942579-100 1x 100 µL
CD10 (Membrane Metalloendopeptidase) (MME/2579), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682305-500 1x 500 µL
FOXA1 / HNF3A (rFOXA1/1515), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742265-500 1x 500 µL
BCL2-like 2 (CPTC-BCL2L2-2), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details