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Insulin Monoclonal Antibody, PE Conjugated

Product Specifications

Background

Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.

Synonyms

ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10.

Gene ID

3630

Host

Mouse

Cross Reactivity

Human

Target

Insulin

Clonality

Monoclonal

Isotype

IgG

Clone

1G11

Conjugation

PE

Source

Recombinant human Insulin protein

Applications

IF (IHC-P), IF (ICC)

Purification

Purified by Protein G.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3630

Predicted Cross Reactivity

Pig

Curated Selection

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