KCNE1 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 5 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr) .
Synonyms
ISK; JLNS; LQT5; MinK; JLNS2; LQT2/5; Potassium voltage-gated channel subfamily E member 1; Delayed rectifier potassium channel subunit IsK; IKs producing slow voltage-gated potassium channel subunit beta Mink; Minimal potassium channel; KCNE1
Gene ID
3753
Swiss Prot
P15382
Cellular Locus
Cytoplasm, Helical
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Dog
Immunogen
41-129/129
Target
KCNE1
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human KCNE1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3753
Curated Selection
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