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KCNE1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 5 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr) .

Synonyms

ISK; JLNS; LQT5; MinK; JLNS2; LQT2/5; Potassium voltage-gated channel subfamily E member 1; Delayed rectifier potassium channel subunit IsK; IKs producing slow voltage-gated potassium channel subunit beta Mink; Minimal potassium channel; KCNE1

Gene ID

3753

Swiss Prot

P15382

Cellular Locus

Cytoplasm, Helical

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Dog

Immunogen

41-129/129

Target

KCNE1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human KCNE1

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3753

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