Glycoprotein VI Polyclonal Antibody

Product Specifications

Background

Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms.

Synonyms

Glycoprotein VI; GP6; GPIV; GPVI; MGC138168; Platelet collagen receptor; Platelet glycoprotein VI; Platelet glycoprotein VI precursor; GPVI_HUMAN.

Gene ID

51206

Swiss Prot

Q9HCN6

Cellular Locus

Extracellular

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

121-220/339

Target

Glycoprotein VI

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GPVI/Glycoprotein VI

Applications

WB, IHC-P, IF (IHC-P)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

51206

Predicted Cross Reactivity

Cow, Pig, Horse

Curated Selection

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