Recombinant Human Annexin A7

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Annexin A7

Gene Name

ANXA7

UniProt

P20073

Reactivity

Human

Target Antigen

Annexin A7

Target

Annexin A7

Type

Protein

Applications

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Form

Liquid

Buffer

20 mM Tris

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. For long-term storage, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze- thaw cycles.

Specificity

Annexin A7

Formulation

Sterile-filtered clear solution (0.25mg/ml) in 20mM Tris-HCl, pH 8.0, 150mM NaCl,1mM DTT, 40% glycerol.

Buffer pH

pH 8.0

Target Background

Annexin 7 is a member of the annexin family of calcium-dependent phospholipids binding proteins. It includes a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter is composed of alternating hydrophobic and hydrophilic segments. Analysis of this protein suggests that Annexin 7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion.