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C3orf70 Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

C3orf70 is a 250 amino acid protein that belongs to the UPF0524 family and is encoded by a gene that maps to human chromosome 3q27.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.

Synonyms

C3orf70; CC070_HUMAN; Chromosome 3 open reading frame 70; hypothetical protein LOC285; UPF0524 protein C3orf70.

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

51-150/250

Target

C3orf70

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human C3orf70

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

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