Sorcin Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Sorcin is a highly conserved protein, with 95% homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin EF hand? motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.
Synonyms
22 kDa protein; Calcium binding protein amplied in mutlidrug resistant cells; CP 22; CP-22; CP22; SCN; Sorcin class 4 gene; Sorcin; SORCN_HUMAN; SRI; V19.
Gene ID
6717
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
131-198/198
Target
Sorcin
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human SR1/Sorcin
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6717
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
124084-APC 100 µL
C19orf10 (UPF0556 Protein C19orf10, Interleukin-25, IL-25, Stromal Cell-derived Growth Factor SF20, IL25, IL27, IL-27, IL27w, R33729_1, SF20, UPF0556 Orotein C19orf10) (APC)
Sign In for Pricing
View Details ARP44367_P050-Biotin 100 µL
Ppic Antibody - N-terminal region : Biotin (ARP44367_P050-Biotin)
Sign In for Pricing
View Details 
MBS6138912-01 0.1 mL
SASH1 (SAM and SH3 Domain-containing Protein 1, KIAA0790, Proline-glutamate Repeat-containing Protein, PEPE1) APC
Sign In for Pricing
View Details