C1orf80 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.
Synonyms
Dorsalization-associated protein; AIDA; AIDA_HUMAN; Axin interaction partner and dorsalization antagonist; Axin interactor; Axin interactor, dorsalization associated; Chromosome 1 open reading frame 80; UPF0491 protein C1orf80.
Gene ID
439927
Host
Rabbit
Cross Reactivity
Human
Immunogen
221-306/306
Target
C1orf80
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human C1orf180/AIDA
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
439927
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Horse, Chicken
Curated Selection
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