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C10orf27 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Synonyms

C10orf27; chromosome 10 open reading frame 27; FLJ32820; Stromal protein associated with thymii and lymph node homolog; stromal protein associated with thymii and lymph nodes; TBATA_HUMAN; SPATIAL; TBATA; thymus, brain and testes associated

Gene ID

219793

Swiss Prot

Q96M53

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

31-130/351

Target

C10orf27

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human C10orf27/SPATIAL

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

219793

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