C10orf27 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
Synonyms
C10orf27; chromosome 10 open reading frame 27; FLJ32820; Stromal protein associated with thymii and lymph node homolog; stromal protein associated with thymii and lymph nodes; TBATA_HUMAN; SPATIAL; TBATA; thymus, brain and testes associated
Gene ID
219793
Swiss Prot
Q96M53
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
31-130/351
Target
C10orf27
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human C10orf27/SPATIAL
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
219793
Curated Selection
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