NHEDC2 Polyclonal Antibody

Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.

NHA2; Mitochondrial Na+/H+ exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na+/H+ exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain containing protein 2; NHE10; NHEDC 2; Sodium/hydrogen exchanger like domain containing protein 2; SL9B2_HUMAN.