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JWA Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

JWA is a four-transmembrane environmental responsive protein which binds to the CC chemokine recepor 5 (CCR5), a major co-receptor for human immunodeficiency virus (HIV) . JWA is involved in environmental stress-responsive pathways in K562 cells, an erythroleukemia cell line derived from patients with chronic myeloid leukemia. Environmental stressors to K562 cells such as heat shock, a higher temperature than the ideal body temperature of the organism from which the cell line was derived, and oxidative stress, the production of oxygen-centered free radicals, regulate and increase the expres-sion of JWA. This response to environmental stressors suggests similiarity of JWA to heat shock protein 70 (HSP70), which is upregulated by heat stress and toxic chemicals.

Synonyms

Addicsin; ADP ribosylation like factor 6 interacting protein 5; Aip 5; Aip5; ARL 6 interacting protein 5; ARL6IP5 antibody Cytoskeleton related vitamin A responsive protein; Dermal papilla derived protein 11; DERP 11; DERP11; Glutamate transporter EEAC 1 associated protein; Glutamate transporter EEAC1 associated protein; GTRAP3 18; Hp 22; Hp22; HSPC 127; HSPC127; JM 5; JM5; JMX; PRA 1 domain family 3; PRA 2; PRA1 domain family 3; PRA2; PRAF 3; PRAF3; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK activating protein PM27; PRAF3_HUMAN.

Gene ID

10550

Host

Rabbit

Immunogen

101-188/188

Target

JWA

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human JWA

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10550

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

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